Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies
نویسندگان
چکیده
BACKGROUND Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressive erosive arthritis with expression of inflammatory mediators and persistence of specific IgM antibodies over 24 months following infection. CONCLUSIONS Understanding the specific features of chikungunya virus as well as how the virus interacts with its host are essential for the prevention, treatment or cure of chikungunya disease.
منابع مشابه
Author's response to reviews Title: Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies Authors:
Denis Malvy ([email protected]) Khaled Ezzedine ([email protected]) Maria Mamani-Matsuda ([email protected]) Brigitte Autran ([email protected]) Hughes Tolou ([email protected]) Marie-Catherine Receveur ([email protected]) Thierry Pistone ([email protected]) Jérôme Rambert (jerome.rambert@u-bordeaux2...
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